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Curriculum Vitae

 

PERSONAL DATA

 

Name: Xin GUAN

Sex: Female

Nationality: P. R. China

Date of Birth: December 31, 1984

Place of Birth: Jinan City, Shandong Province, P. R. China

Academic title: Doctor

Institute: College of Horticulture and Landscape Architecture, Southwest University, P. R. China

 

         

E-mail: xinguan.cnde@googlemail.com; xin.guan@swu.edu.cn

Website: http://xinguancnde.lingw.net/

Telephone: +86-(0)-23-6825-1047

Mailing address:

西南大学园艺园林学院中国重庆市北碚区天生路2邮编400700

(College of Horticulture and Landscape Architecture, Southwest University, Tianshenglu 2, Beibei, 400700, Chongqing, P. R. China)

 

EDUCATION

 

l  09.2010 – 07.2013 Ph. D. Sc., Molecular Cell Biology, Botanical Institute, Chemistry and Bioscience, Karlsruhe Institute of Technology, Karlsruhe, Germany.

Supervisor: Prof. Dr. Peter Nick

Thesis: Functional Analysis of Cytoskeletal Signalling in the Defence Response of Grapevine

 

l  09.2007 – 06.2010 M. Agri., College of Horticulture, Northwest A&F University, P. R. China.

Supervisor: Prof. Dr. Yuejin Wang

Thesis: A Study of the Genetic Transformation of Susceptible Grapes with a Novel Glyoxal Oxidase Related Gene from Chinese Wild Vitis pseudoreticulata

 

l  09.2003 – 06.2007 B. Agri., College of Horticulture, Qingdao Agriculture University, P. R. China.

Supervisor: Prof. Dr. Yongzhang Wang

Thesis: Growth Development and Observation of Ultrastructure on 'Hongdeng' Sweet Cherry. Review of a Study on Influences on Fruit under the Microenvironment of Bagging

 

WORKING EXPERIENCE


l  06.2016 – present Associate Professor, College of Horticulture and Landscape Architecture, Southwest University, Tianshenglu 2, Beibei, 400700, Chongqing, P. R. China

l  09.2013 – 06.2016 Lecturer, College of Horticulture and Landscape Architecture, Southwest University, Tianshenglu 2, Beibei, 400700, Chongqing, P. R. China

In team of: Prof. Dr. Zhiqin Zhou

Main research: Functional analysis of Citrus fruit bioactive compounds and evaluation of health benefits.

l  12.2013 – 12.2015 Postdoc, Laboratoire Vigne Biotechnologies et Environnement EA-3991, Université de Haute-Alsace, Colmar, France.

Supervisor: Prof. Dr. Christophe Bertsch

Main research: Cytoskeleton and grapevine trunk disease.

 

RESEARCH EXPERIENCE

 

09/2013-present

 

 

 

 

12/2013-09/2015

 

09/2010-07/2013

 

 

 

 

 

 

 

05/2007-06/2010

Studies of the regulation of   bioactive compounds from Citrus fruit on cytoskeletal signaling in yeast and   mammalian cells

 

A net work on MTs involved in plant early innate   immunity

 

Plant cytoskeleton   and grapevine drunk disease

 

The cytoskeleton   responses in two ways of plant innate immunity: PAMP-triggered immunity v.s.   Effector-triggered immunity in tobacco BY-2 cells

 

Microtubule of   grapevine responses to biotic and abiotic challenge

 

Actin filament   of grapevine stomata responses to pathogen

 

Transient   expression of glyoxal oxidase from the Chinese wild grape Vitis pseudoreticulata challenged by   Powdery Mildew in a susceptible genotype

 

Characterization   of novel gene expression related to glyoxal oxidase by agro-infiltration of   the leaves of accession Baihe-35-1 of Vitis   pseudoreticulata involved in production of H2O2 for   resistance to Erysiphe necator

 

Studies on genetic   transformation of grape shoot apical meristems by Agrobacterium-mediated transformation

 

05/2008-02/2009

Cloning   and functional analysis of a stilbene synthase-specific promoter from Chinese wild Vitis species

 

05/2008-06/2010

Germplasm innovation   of seedless grapevine by embryo rescue

 

08/2007-07/2009

Localization   of stilbene synthase in Chinese wild Vitis   leaves after inoculating with downy mildew

 

10/2006-06/2007

Growth   development and observation of ultrastructures on ‘Hongdeng’ Sweet Cherry

 

RESEARCH INTERESTS

 

Runing projects (as the leader in SW Uni in China):

1.                   Project “Studies of the regulation of bioactive compounds from Citrus fruit on cytoskeletal signalling in plant and animal” founded by Science Foundation of Ministry of Education of China (12.2013-12.2016).

2.                   Project “Characterization of antioxidant activity of Citrus fruits on potential health-promoting properties” founded by Fundamental Research Funds for the Central Universities (03.2014-03.2017).

3.                   Project “The early signalling transduction of microtubule during infection of Citrus tristeza virus” founded by National training programs of innovation and entrepreneurship for undergraduates (05.2015-11.2016).

4.                   Project “Study on the training model of the international exchange including bilingual teaching and scientific research cooperation in the Sino-French colleges for M. Agri.” (07.2015-07.2018).

 

PUBLICATIONS

 

·         Si Tan, Xin Guan (contribution equally), Christoph gruen, Zhiqin Zhou, Ute Schepers, Peter Nick. 2015. Gallic acid induces mitotic catastrophe and inhibits centrosomal clustering in HeLa cells. Toxicology in Vitro. http://dx.doi.org/10.1016/j.tiv.2015.09.011

 

·         Xin Guan, Salwa Essakhi, Helene Laloue, Peter Nick, Christophe Bertsch, Julie Chong. 2015. Mining new resources for grape resistance against Botryosphaeriaceae: a focus on Vitis vinifera ssp. sylvestris. Plant Pathology. DOI: 10.1111/ppa.12405

 

·         Xin Guan, Günther Buchholz, Peter Nick. 2015. Tubulin marker line of grapevine suspension cells as a tool to follow early stress responses. Journal of Plant Physiology. 176: 118–128

 

·         Xin Guan, Günther Buchholz, Peter Nick. 2014. Actin marker lines in grapevine reveal a gatekeeper function of guard cells. Journal of Plant Physiology, 171: 1164-1173

 

·         Xin Guan, Heqing Zhao, Yan Xu, Yuejin Wang. 2013. Studies on genetic transformation of grape shoot apical meristems by Agrobacterium-mediated transformation. Vitis, 52: 185-192.

 

·         Xin Guan, Günther Buchholz, Peter Nick. 2013. The cytoskeleton is disrupted by the bacterial effector HrpZ, but not by the bacterial PAMP flg22 in tobacco BY-2 cells. Journal of Experimental Botany, 64: 1805-1816.

 

·         Heqing Zhao, Xin Guan (contribution equally), Yan Xu, Yuejin Wang. 2012. Characterization of novel gene expression related to glyoxal oxidase by agro-infiltration of the leaves of accession Baihe-35-1 of Vitis pseudoreticulata involved in production of H2O2 for resistance to Erysiphe necator. Protoplasma, 250: 765-777.

 

·         Mingyang He, Yan Xu, Jiangling Cao, Ziguo Zhu, Yuntong Jiao, Yuejin Wang, Xin Guan, Yazhou Yang, Weirong Xu and Zhenfang Fu. 2012. Subcellular localization and functional analyses of a PR10 protein gene from Vitis pseudoreticulata in response to Plasmopara viticola infection. Protoplasma, 250: 129-140.

 

·         Xin Guan, Heqing Zhao, Yan Xu, Yuejin Wang. 2011. Transient expression of glyoxal oxidase from the Chinese wild grape Vitis pseudoreticulata can suppress Powdery Mildew in a susceptible genotype. Protoplasma, 248: 415-423.

 

SCHOLARSHIPS AND HONORS

 

l  07/2014-present Editor, Horticultural Plant Journal, China; Journal of Molecular Biology and Molecular Imaging, Austin Publishing Group, USA

l  12/2013-12/2014 Postdoc research, BACCHUS Interreg project (Upper-Rhine Region: Rheinland-Pfalz, Baden-Württemberg, the Alsace and the Basel-Region), Colmar, France

l  02/2013-07/2013 Research assistantships, Deutsche Akademische Austausch Dienst (DAAD)-STIBET-program, Karlsruhe Institute of Technology, Karlsruhe, Germany

l  09/2010-09/2013 Scholarship under the China State Scholarship Fund (China Scholarship Council), Karlsruhe Institute of Technology, Karlsruhe, Germany

l  2008 Excellent postgraduate student, Northwest A&F University, Yangling, China

l  2006 Excellent undergraduate student, Qingdao Agriculture University, Qingdao, China

 

POSTERS AND ORAL PRESENTATIONS

 

l  July 2nd, 2015 Plant Biotic Stresses & Resistance Mechanisms (Vienna, Austria) Poster: Cytoskeleton marker lines of grapevine as tools to follow early biotic stress responses

l  July 28th, 2014 11th International Conference on Grapevine Breeding and Genetics (Beijing, China), Poster: Actin marker lines in grapevine reveal a gatekeeper function of guard cells

l  May 15th, 2014 9th Rhein-Wein Symposium (Karlsruhe, Germany), Oral presentation: Grapevine trunk disease

l  Oct 21st, 2013 The 12nd National Congress & Annual Academic Conference of Chinese Society for Horticultural Science (Chengdu, China), Oral presentation: Cytoskeletal and plant defense, grapevine as a model

l  May 17th, 2013 8th Rhein-Wein Symposium (Karlsruhe, Germany), Oral presentation: Cytoskeletal marker lines in grapevine: where can we go?

l  Feb 21st, 2013 Plant Diseases and Resistance Mechanisms (Vienna, Austria), Poster: Stomata guarding roles superior to epidermal cells – directed by grapevine Actin filaments

l  Jan 21st, 2013 spinning-disc confocal microscopy pics of Vitis cytoskeleton accepted as post card and flyer by BACCHUS Interreg project (Freiburg, Germany)

l  Sep 12nd, 2012 Black Forest Retreat on Molecular Plant Science (Herzogenhorn, Germany), Oral presentation: Cytoskeleton and stress responses of crop plants: grapevine as model

l  May 3rd, 2012 7th Rhein-Wein Symposium (Karlsruhe, Germany), Oral presentation: Cytoskeletal signalling in the defense response of grapevine

l  May 2nd, 2012 Feasibility Studies of Young Scientist – independent project proposal (Karlsruhe, Germany), Oral presentation: Establishment of a fluorescently tagged marker line for the grapevine pathogen Plasmopara viticola

l  March 22nd, 2012 3rd KIT PhD Symposium (Karlsruhe, Germany), Poster: The cytoskeleton and the two ways of plant immunity -- PAMP-triggered immunity v.s. Effector-triggered immunity

 

TEACHING EXPERIENCE

 

l  09/2015-01/2016 lecturer, a. Horticulture in English; b. How to use reference papers; c. fruit quality and nutrition; d. Introduction of advanced methodology to study horticulture (Department of Horticulture and Landscape, Southwest University, China)

l  03/2015-09/2015 co-supervisor with Prof. Christophe Bertsch and Prof. Zhiqin Zhou for French master student, Study on the metabolite profiling of Citrus and Vitis suspension cell lines after infection by fungi of the Botryosphaeriaceae family (Department of Horticulture and Landscape, Southwest University, China)

l  12/2013-12/2014 co-supervisor with Prof. Peter Nick and Prof. Zhiqin Zhou for Chinese Ph.D. student, Bioactive compounds from Citrus fruit on cytoskeletal signaling in plant and mammalian cells (Laboratory of Grapevine, Biotechnology and Environment, Haute-Alsace University, Colmar, France)

l  10/2012-11/2012 Teaching assistance Phytohormone (Botanic institute, molecular cell biology, Karlsruhe Institute of Technology, Germany)

l  04/2011-05/2011 Teaching assistance Immunofluorescence (Botanic institute, molecular cell biology, Karlsruhe Institute of Technology, Germany)

l  04/2012-05/2012 Teaching assistance Immunofluorescence (Botanic institute, molecular cell biology, Karlsruhe Institute of Technology, Germany)

 


个人简历

 

基本信息

 

姓名:关心

性别:

出生日期:1984.12.31

籍贯:山东济南

政治面貌:中共党员

学历:博士

专业:分子细胞生物学

 

单位:西南大学 园艺园林学院, 中国 重庆

电子邮件:xinguan.cnde@googlemail.com; xin.guan@swu.edu.cn

个人网站:http://xinguancnde.lingw.net/

电话+86-(0)-23-6825-1047

地址西南大学,园艺园林学院,重庆市北碚区,天生路2号,邮编400700

 

教育背景

 

l  2010.09–2013.07理学博士,卡尔斯鲁厄理工学院,化学与生命科学学院,分子生物细胞学植物研究所,德国 卡尔斯鲁厄

导师:Peter Nick 教授
毕业论文:植物细胞骨架在葡萄抗性过程中的信号转导及功能分析 [英文]

l  2007.09–2010.06农学硕士,西北农林科技大学 园艺学院

导师:王跃进 教授
毕业论文:中国野生华东葡萄新基因乙二醛氧化酶基因遗传转化部分葡萄的研究

l  2003.09–2007.06农学学士,青岛农业大学 园艺学院

导师:王永章 教授
毕业论文红灯大樱桃果实发育过程中超微结构研究

工作经历

 

l  2016.06至今 副教授,西南大学 园艺园林学院

l  2013.09-2016.06 讲师,西南大学 园艺园林学院

所在团队:周志钦 教授
研究课题:柑橘果实活性物质与酵母、哺乳动物细胞骨架信号转导

l  2013.12-2015.12 博士后,葡萄、生物技术与环境实验室,上阿尔萨斯州大学,法国 科尔玛

导师:Christophe Bertsch 教授
研究课题:植物细胞骨架与葡萄树干真菌病害

 

研究经历

 

2013.09至今

 

 

 

 

2013.12-2015.12

 

2010.092013.07

 

 

 

 

 

 

 

柑橘果实活性物质对植物、哺乳动物细胞骨架在生物与非生物胁迫下信号转导中的调控研究

 

微管蛋白在植物内源免疫早期阶段的调控

 

植物细胞骨架与葡萄树干真菌病害

 

植物细胞骨架在内源免疫两个层面中的作用:烟草BY-2细胞悬浮系中病原相关分子模式诱发的免疫与效应因子诱发的免疫

 

葡萄悬浮细胞系中微管对生物及非生物胁迫的反应

 

保卫细胞的门卫作用:葡萄气孔保卫细胞中微丝对病原的反应

 

建立荧光标记的葡萄霜霉病菌(德国学术交流中心(DAAD)-STIBET项目)

 

中国野生华东葡萄感病基因型的乙二醛氧化酶基因在抗白粉菌过程中瞬时表达分析

 

通过农杆菌介导的瞬时表达研究过氧化氢生物合成途径中中国野生华东葡萄白河-35-1乙二醛氧化酶新基因的功能

 

农杆菌介导法遗传转化中国野生华东葡萄茎顶端分生组织的研究

 

2007.082010.07

 

 

 

 

 

 

 

 

2008.052009.02

中国野生华东葡萄芪合成酶基因特异启动子克隆与功能分析

 

2008.052010.06

通过胚挽救创造无核葡萄新种质

 

2007.082009.07

中国野生葡萄芪合成酶基因对霜霉菌诱导的定位分析

 

2006.102007.06

红灯大樱桃果实发育过程中的超微结构研究

 

在研项目

 

西南大学(项目主持)

1.西南大学引进人才科研项目SWU113107:教育部专项“柑橘果实活性物质对植物、酵母细胞骨架信号转导中的调控研究”(12.2013-12.2016)

2.西南大学基本科研业务费专项“创新团队”任务XDJK2014A014:“柑橘全果抗氧化活性评价及其利用研究”(03.2014-03.2017)

3.国家级大学生创新训练项目(指导教师)201510635033:“柑橘细胞微管蛋白在柑橘衰退病病毒侵染过程中的早期信号转导调控研究”(05.2015-11.2016)

4.重庆市研究生教育教学改革研究项目yjg153078:“全日制学术型硕士中法院际互换与联合培养模式研究”(07.2015-07.2018)

 

发表文章

 

·         Si Tan, Xin Guan (contribution equally), Christoph gruen, Zhiqin Zhou, Ute Schepers, Peter Nick. 2015. Gallic acid induces mitotic catastrophe and inhibits centrosomal clustering in HeLa cells. Toxicology in Vitro. http://dx.doi.org/10.1016/j.tiv.2015.09.011

 

·         Xin Guan, Salwa Essakhi, Helene Laloue, Peter Nick, Christophe Bertsch, Julie Chong. 2015. Mining new resources for grape resistance against Botryosphaeriaceae: a focus on Vitis vinifera ssp. sylvestris. Plant Pathology. DOI: 10.1111/ppa.12405

·         Xin Guan, Günther Buchholz, Peter Nick. 2015. Tubulin marker line of grapevine suspension cells as a tool to follow early stress responses. Journal of Plant Physiology, 176: 118–128.

 

·         Xin Guan, Günther Buchholz, Peter Nick. 2014. Actin marker lines in grapevine reveal a gatekeeper function of guard cells. Journal of Plant Physiology, 171: 1164-1173

 

·         Xin Guan, Heqing Zhao, Yan Xu, Yuejin Wang. 2013. Studies on genetic transformation of grape shoot apical meristems by Agrobacterium-mediated transformation. Vitis, 52: 185-192.

 

·         Xin Guan, Günther Buchholz, Peter Nick. 2013. The cytoskeleton is disrupted by the bacterial effector HrpZ, but not by the bacterial PAMP flg22 in tobacco BY-2 cells. Journal of Experimental Botany, 64: 1805-1816.

 

·         Heqing Zhao, Xin Guan (contribution equally), Yan Xu, Yuejin Wang. 2012. Characterization of novel gene expression related to glyoxal oxidase by agro-infiltration of the leaves of accession Baihe-35-1 of Vitis pseudoreticulata involved in production of H2O2 for resistance to Erysiphe necator. Protoplasma, 250: 765-777.

 

·         Mingyang He, Yan Xu, Jiangling Cao, Ziguo Zhu, Yuntong Jiao, Yuejin Wang, Xin Guan, Yazhou Yang, Weirong Xu and Zhenfang Fu. 2012. Subcellular localization and functional analyses of a PR10 protein gene from Vitis pseudoreticulata in response to Plasmopara viticola infection. Protoplasma, 250: 129-140.

 

·         Xin Guan, Heqing Zhao, Yan Xu, Yuejin Wang. 2011. Transient expression of glyoxal oxidase from the Chinese wild grape Vitis pseudoreticulata can suppress Powdery Mildew in a susceptible genotype. Protoplasma, 248: 415-423.

 

个人荣誉

 

l  2014.07至今 编辑,园艺学报英文版,中国;分子生物学与分子生物成像期刊,美国

l  2013.12-2015.12 博士后研究,上莱茵河地区德国、法国、瑞士巴克斯联合项目BACCHUS,上阿尔萨斯州大学,法国 科尔玛

l  2013.02–2013.07 科研助理,德国学术交流中心(DAAD)-STIBET项目,卡尔斯鲁厄理工学院,德国 卡尔斯鲁厄

l  2010.09–2013.09 中国国家建设高水平大学公派研究生项目,卡尔斯鲁厄理工学院,德国 卡尔斯鲁厄

l  2008 优秀研究生,西北农林科技大学,中国 杨凌

l  2006 优秀本科生,青岛农业大学,中国 青岛

 

语言能力

 

汉语、英语:听说读写;德语、法语:基础听说读。

 

参加会议

 

l  2015.07.02 植物生物胁迫与抗性机制(奥地利 维也纳)参会海报:葡萄细胞骨架标记系作为有利工具可研究早期生物胁迫

l  2014.07.28 第十一届国际葡萄遗传与育种大会(中国 北京)参会海报:葡萄微丝荧光蛋白表达植株揭示了气孔保卫细胞的门卫作用

l  2014.05.15第九届莱茵河葡萄大会 (德国 卡尔斯鲁厄), 会议发言:葡萄树干真菌病害

l  2013.10.21 中国园艺学会第十二次会员代表大会暨学术年会(中国 成都),会议发言:植物细胞骨架对生物胁迫的调控,模式植物葡萄

l  2013.05.17第八届莱茵河葡萄大会(德国 卡尔斯鲁厄),会议发言:葡萄转基因微丝标记植株:如何更好地利用?

l  2013.02.11 植物病理与抗性机制(奥地利 维也纳),参会海报:气孔胜于表皮细胞的保卫作用--葡萄微丝的调控

l  2013.01.21 葡萄细胞骨架转牒共聚焦显微镜照片被上莱茵河地区德国法国瑞士巴克斯联合项目接收,设计为大会明信片和宣传手册 (德国 弗莱堡)

l  2012.09.12 植物分子生物学黑森林地区大会 (德国 赫左根霍恩),会议发言:经济作物的细胞骨架与抗性反应:模式植物葡萄

l  2012.05.03 第七届莱茵河葡萄大会 (德国 卡尔斯鲁厄), 会议发言:葡萄细胞骨架在抗性反应中的信号转导

l  2012.05.02 德国青年科学家可行性独立研究项目论证 (德国 卡尔斯鲁厄),会议发言:建立荧光标记的葡萄霜霉病菌

l  2012.03.22 第三届卡尔斯鲁厄理工学院博士生论坛 (德国 卡尔斯鲁厄), 参会海报:植物细胞骨架在内源免疫两个层面中的作用:烟草BY-2细胞悬浮系中病原相关分子模式诱发的免疫与效应因子诱发的免疫

 

教学

 

l  2015.09-2016.01 本科教学 园艺专业英语;研究生教学 中外主文献研读、果品品质与营养、现代园艺学研究方法导论(西南大学,园艺园林学院)

l  2014.03-2014.09 法国硕士研究生合作导师(Prof. Christophe Bertsch, 周志钦教授)葡萄座腔菌属真菌对寄主和非寄主细胞的代谢调控(西南大学,园艺园林学院)

l  2013.12至今 中国博士研究生合作导师(Prof. Peter Nick, 周志钦教授)柑橘果实活性物质在植物、哺乳动物细胞骨架信号转导中的调控研究上阿尔萨斯州大学,葡萄、生物技术与环境实验室,法国

l  2012.092012.10 德国硕士研究生教学 植物激素调控 (分子细胞生物学植物研究所,卡尔斯鲁厄理工学院,德国)

l  2012.042012.05 德国本科生教学 免疫荧光化学 (分子细胞生物学植物研究所,卡尔斯鲁厄理工学院,德国)

l  2011.042011.05 德国本科生教学 免疫荧光化学 (分子细胞生物学植物研究所,卡尔斯鲁厄理工学院,德国)